История изменений

А ты не смотри псевдонаучные фильмы.

One of the most persuasive arguments for the importance of intrinsic activity emerges from a consideration of its relative cost in terms of brain energy consumption. In the average adult human, the brain represents about 2% of the total body weight yet it accounts for 20% of all the energy consumed [6], 10 times that predicted by its weight alone. Relative to this very high rate of ongoing energy consumption in the resting state (Box 1), the additional energy consumption associated with changes in brain activity is remarkably small, often less than5%(Figure 1). Fromthese data it is clear that the brain’s enormous energy consumption is little affected by task performance, an observation first made more than 50 years ago by Louis Sokoloff, Sey- mour Kety and their colleagues [7] but rarely cited. What is the nature of this ongoing intrinsic activity that commands such a large amount of the brain’s energy resources? Assessments of brain energy metabolism using a variety of approaches ([8–12] for review see [13]) indicate that from 60 to 80% of overall brain energy consumption is devoted to glutamate cycling and, hence, neural signaling processes. Such estimates leave for future consideration the demands placed on the brain’s energy budget by the activity of inhibitory interneurons [14–19] and astrocytes [20,21]. That evidence notwithstanding it is probable that the majority of brain energy consumption is devoted to functionally significant intrinsic activity.

Raichle, M. E. (2010). Two views of brain function. Trends in Cognitive Sciences, 14(4), 180–90. doi:10.1016/j.tics.2010.01.008

А ты не смотри псевдонаучные фильмы.

Cost One of the most persuasive arguments for the importance of intrinsic activity emerges from a consideration of its relative cost in terms of brain energy consumption. In the average adult human, the brain represents about 2% of the total body weight yet it accounts for 20% of all the energy consumed [6], 10 times that predicted by its weight alone. Relative to this very high rate of ongoing energy consumption in the resting state (Box 1), the additional energy consumption associated with changes in brain activity is remarkably small, often less than5%(Figure 1). Fromthese data it is clear that the brain’s enormous energy consumption is little affected by task performance, an observation first made more than 50 years ago by Louis Sokoloff, Sey- mour Kety and their colleagues [7] but rarely cited. What is the nature of this ongoing intrinsic activity that commands such a large amount of the brain’s energy resources? Assessments of brain energy metabolism using a variety of approaches ([8–12] for review see [13]) indicate that from 60 to 80% of overall brain energy consumption is devoted to glutamate cycling and, hence, neural signaling processes. Such estimates leave for future consideration the demands placed on the brain’s energy budget by the activity of inhibitory interneurons [14–19] and astrocytes [20,21]. That evidence notwithstanding it is probable that the majority of brain energy consumption is devoted to functionally significant intrinsic activity.

Raichle, M. E. (2010). Two views of brain function. Trends in Cognitive Sciences, 14(4), 180–90. doi:10.1016/j.tics.2010.01.008

А ты не смотри псевдонаучные фильмы.

Adjudicating the merits of intrinsic activity Cost One of the most persuasive arguments for the importance of intrinsic activity emerges from a consideration of its relative cost in terms of brain energy consumption. In the average adult human, the brain represents about 2% of the total body weight yet it accounts for 20% of all the energy consumed [6], 10 times that predicted by its weight alone. Relative to this very high rate of ongoing energy consumption in the resting state (Box 1), the additional energy consumption associated with changes in brain activity is remarkably small, often less than5%(Figure 1). Fromthese data it is clear that the brain’s enormous energy consumption is little affected by task performance, an observation first made more than 50 years ago by Louis Sokoloff, Sey- mour Kety and their colleagues [7] but rarely cited. What is the nature of this ongoing intrinsic activity that commands such a large amount of the brain’s energy resources? Assessments of brain energy metabolism using a variety of approaches ([8–12] for review see [13]) indicate that from 60 to 80% of overall brain energy consumption is devoted to glutamate cycling and, hence, neural signaling processes. Such estimates leave for future consideration the demands placed on the brain’s energy budget by the activity of inhibitory interneurons [14–19] and astrocytes [20,21]. That evidence notwithstanding it is probable that the majority of brain energy consumption is devoted to functionally significant intrinsic activity.

Raichle, M. E. (2010). Two views of brain function. Trends in Cognitive Sciences, 14(4), 180–90. doi:10.1016/j.tics.2010.01.008

А ты не смотри псевдонаучные фильмы.

Adjudicating the merits of intrinsic activity Cost One of the most persuasive arguments for the importance of intrinsic activity emerges from a consideration of its relative cost in terms of brain energy consumption. In the average adult human, the brain represents about 2% of the total body weight yet it accounts for 20% of all the energy consumed [6], 10 times that predicted by its weight alone. Relative to this very high rate of ongoing energy con-

sumption in the resting state (Box 1), the additional energy consumption associated with changes in brain activity is remarkably small, often less than5%(Figure 1). Fromthese data it is clear that the brain’s enormous energy consump- tion is little affected by task performance, an observation first made more than 50 years ago by Louis Sokoloff, Sey- mour Kety and their colleagues [7] but rarely cited. What is the nature of this ongoing intrinsic activity that commands such a large amount of the brain’s energy resources? Assessments of brain energy metabolism using a variety of approaches ([8–12] for review see [13]) indicate that from 60 to 80% of overall brain energy consumption is devoted to glutamate cycling and, hence, neural signaling processes. Such estimates leave for future consideration the demands placed on the brain’s energy budget by the activity of inhibitory interneurons [14–19] and astrocytes [20,21]. That evidence notwithstanding it is probable that the majority of brain energy consumption is devoted to functionally significant intrinsic activity.

Raichle, M. E. (2010). Two views of brain function. Trends in Cognitive Sciences, 14(4), 180–90. doi:10.1016/j.tics.2010.01.008